NUCLEO FORTE INYECTABLE SKIN

In an application with anticonvulsant drugs decreased cyanocobalamin absorption from the gut. In an application of Nucleo CMP (Vitamin B12 (Hydroxocobalamin)) with hormonal contraceptives for oral administration may decrease the concentration of cyanocobalamin in plasma.

Nucleo CMP (Vitamin B12 (Hydroxocobalamin)) drug interactions It is unacceptable to enter in the same syringe with cyanocobalamin solutions of thiamine and pyridoxine. During treatment should regularly monitor the blood picture and coagulation. When stenocardia should be used with caution in a single dose of Nucleo CMP ) 100 mcg. Nucleo CMP ) using during pregnancy and breastfeedingД¬yanocobalamin can be used in pregnancy according to prescriptions.

Thromboembolism, erythremia, erythrocytosis, increased sensitivity to cyanocobalamin. Nucleo CMP (Vitamin B12 (Hydroxocobalamin)) side effects, adverse reactionsД¬ardiovascular system: rarely - pain in the heart, tachycardia. Duration of treatment is determined individually. When deficiency of Nucleo CMP (Vitamin B12 (Hydroxocobalamin)) to prevent - IV or IM for 1 mg 1 time a month for treatment - IV or IM for 1 mg daily for 1-2 weeks, the maintenance dose is 1-2 mg IV or IM from 1 per week, up to 1 per month. In radiation sickness, diabetic neuropathy, sprue - by 60-100 mcg daily for 20-30 days. When funicular myelosis, amyotrophic lateral sclerosis can be introduced into the spinal canal at 15-30 mcg, gradually increasing the dose of 200-250 micrograms. When hepatitis and cirrhosis - 30-60 mcg / day or 100 mg every other day for 25-40 days.Дystrophy in young children, Down syndrome and cerebral palsy - by 15-30 mcg every other day. In traumatic lesions of peripheral nervous system - at 200-400 mcg every other day for 40-45 days. The course of treatment with Nucleo CMP (Vitamin B12 (Hydroxocobalamin)) is 2 weeks. In diseases of the central and peripheral nervous system and neurological diseases with a pain syndrome is administered in increasing doses - 200-500 mcg, with the improvement in the state - 100 mcg / day. When nutritional anemia in infants and preterm - 30 mcg / day during 15 days. When aplastic anemia (especially in children) - 100 micrograms before clinical improvement. In acute post-hemorrhagic anemia and iron anemia by 30-100 mcg 2-3 times a week. In the period of remission in the absence of events funicular myelosis maintenance dose - 100 mcg 2 times a month, in the presence of neurological symptoms - at 200-400 mcg 2-4 times a month. In anemia with symptoms of funicular myelosis and megalocytic anemia with diseases of the nervous system - 400-500 micrograms in the first 7 days daily, then 1 time every 5-7 days. With anemia associated with Nucleo CMP (Vitamin B12 (Hydroxocobalamin)) deficiency is introduced on 100-200 mcg in 2 days. Nucleo CMP ) is used as injections SC, IV, IM, intralumbar, and also oral.

NUCLEO FORTE INYECTABLE SKIN

Excreted in bile and urine.ДЄnemia due to B12-deficiency conditions in the complex therapy for iron and posthemorrhagic anemia aplastic anemia caused by toxic substances and drugs liver disease (hepatitis, cirrhosis) funicular myelosis polyneuritis, radiculitis, neuralgia, amyotrophic lateral sclerosis children cerebral palsy, Down syndrome, peripheral nerve injury skin diseases (psoriasis, photodermatosis, herpetiformis dermatitis, neurodermatitis) to prevent and treat symptoms of deficiency of Nucleo CMP (Vitamin B12 (Hydroxocobalamin)) (including the application of biguanide, PASA, vitamin C in high doses) radiation sickness. Metabolized in the tissues, becoming a co-enzyme form - adenosylcobalamin which is the active form of cyanocobalamin. Activates the coagulation of blood in high doses causes an increase in the activity of thromboplastin and prothrombin.ДЄfter oral administration Nucleo CMP (Vitamin B12 (Hydroxocobalamin)) absorbed from the gastrointestinal tract. Has a beneficial effect on liver function and the nervous system. Contributes to the accumulation in erythrocytes of compounds containing sulfhydryl groups. Involved in the processes of transmethylation, hydrogen transport, synthesis of methionine, nucleic acids, choline, creatine. Nucleo CMP (Vitamin B12 (Hydroxocobalamin)) is necessary for normal hematopoiesis (promotes maturation of erythrocytes). Nucleo CMP ) refers to a group of water-soluble vitamins.

Nucleo forte inyectable